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Sexual function after long term adt

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149 18.07.2019
In a population-based study reported in The Lancet Oncology , Downing et al found little difference in health-related quality of life HRQOL between men with advanced vs localized prostate cancer. Sexual function problems were common among all patients—and often not addressed—and use of androgen-deprivation therapy ADT was associated with greater toxicity. The study involved 35, survey respondents of 58, mailed surveys among men in the U. Among 30, with known disease stage, 19, The survey contained measures to assess functional outcomes urinary incontinence; urinary irritation and obstruction; bowel, sexual, and vitality and hormonal function measured with the Expanded Prostate Cancer Index Composite short form EPIC , questions regarding use of interventions for sexual dysfunction, and generic HRQOL assessed with the 5-level EuroQol five dimensions questionnaire EQ-5D measuring mobility, self-care, usual activities, pain or discomfort, and anxiety or depression, plus a rating of self-assessed health. Models comparing outcomes were adjusted for age, socioeconomic deprivation, and number of other long-term conditions.
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ADT Affects Sexual Function, Intimacy in Early Prostate Cancer Treatment

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Prostate Cancer: Types of Treatment | stihotvorenia.com

Some of the most common side effects of ADT — a frequently used treatment for prostate cancer that lowers testosterone to castration levels — include mood depression and sexual dysfunction. Although the impact on individual patients has been well established, the impact on the patient-partner sexual relationship and intimacy has not been fully explored. For this study, researchers evaluated the outcomes of 72 men on ADT and their partners. Couples completed questionnaires evaluating prostate cancer health-related quality of life, sexual function eg, desire, erection, orgasm, overall function , sexual bother bother associated with aspects of sexual function , and mood eg, tension, depression, anger, vigor, fatigue, confusion. Measures were assessed over time, starting at baseline, then 3 months and 6 months after initiating ADT. Results showed that there were declines in sexual function, frequency, and relational intimacy during the first 6 months of ADT; Sexual bother significantly increased between baseline and 3 months only.
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Surgery and hormonal treatment for prostate cancer and sexual function

Skip to Content. Use the menu to see other pages. This section tells you the treatments that are the standard of care for this type of cancer. When making treatment plan decisions, patients are encouraged to consider clinical trials as an option.
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Facts about Prostate Cancer: Prostate cancer is a highly prevalent disease afflicting one in five American men. It is the most commonly diagnosed cancer in men and the second leading cause of cancer death after lung cancer. Treatments for advanced prostate cancer: Androgen ablation and Chemotherapy. A survey was mailed to men with prostate cancer by either radiation therapy or radical prostatectomy. The following results were obtained.

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